SCHEMBL4001708

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8748004	0.85	ALDH1A1 (0.59)	RAB9ARXFP1MAPTSMN1; SMN2CA1
	SCHEMBL9812449	0.79	RAB9A (0.51)	RAB9ANPC1RXFP1PPARGNR2E3
	SCHEMBL18900607	0.78	ALDH1A1 (0.51)	RAB9ANPC1RXFP1PPARGNR2E3
	SCHEMBL1134428	0.78	ALDH1A1 (0.55)	RAB9ANPC1MAPTSMN1; SMN2CA12
	SCHEMBL27333040	0.76	ALDH1A1 (0.53)	RAB9ANPC1MAPTSMN1; SMN2CA12
	Hydrochloric Acid SCHEMBL28095718	0.76	ALDH1A1 (0.53)	RAB9ANPC1MAPTSMN1; SMN2CA12
	SCHEMBL21568088	0.76	MAPT (0.71)	RAB9ANPC1MAPTSMN1; SMN2GAA
	SCHEMBL9449429	0.72	CA2 (0.77)	RXFP1MAPTCA12CA1CA2
	SCHEMBL28203165	0.72	ALDH1A1 (0.50)	RAB9ANPC1MAPTSMN1; SMN2CA12
	SCHEMBL11859460	0.71	CA1 (0.70)	RAB9ANPC1MAPTCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.