SCHEMBL400236

SCHEMBL400236

BrCc1cc(Br)cc(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.46
TSHR P16473 2/20 0.38
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TAAR1 Q96RJ0 1/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
AGXT P21549 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL642402 0.93 IDO1 (0.40) IDO1TSHRTRPA1ALDH1A1TAAR1
SCHEMBL9616495 0.87 IDO1 (0.38) IDO1TSHRTRPA1ALDH1A1
SCHEMBL671058 0.81 IDO1 (0.34) IDO1TSHRTRPA1ALDH1A1
SCHEMBL10448080 0.81 IDO1 (0.33) IDO1TSHRTRPA1ALDH1A1
SCHEMBL29999249 0.81 TSHR (0.40) IDO1TSHRTRPA1ALDH1A1CYP3A4
SCHEMBL24661052 0.81 IDO1 (0.38) IDO1TSHRTRPA1ALDH1A1TAAR1
SCHEMBL13973047 0.81 ACHE (0.40) IDO1TSHRTRPA1ALDH1A1CYP3A4
SCHEMBL30349373 0.81 TACR1 (0.41) IDO1TSHRTRPA1ALDH1A1
SCHEMBL29472374 0.81 IDO1 (0.34) IDO1TSHRTRPA1ALDH1A1
SCHEMBL8447346 0.81 IDO1 (0.33) IDO1TSHRTRPA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067347-A1 PHAGE PARTICLE COMPLEX, PREPARATION METHOD THEREFOR, AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2025-04-03 WO claimed
CN-103943805-A Lithium ion secondary battery and diaphragm thereof NINGDE AMPEREX TECHNOLOGY LTD 2014-07-23 CN claimed
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BOLT BIOTHERAPEUTICS, INC. (US) 2026-03-10 US disclosed
EP-4629980-A1 ANTIMICROBIAL COMPOUNDS SRI International (US) 2025-10-15 EP disclosed
US-20250263392-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2025-08-21 US disclosed
WO-2025104079-A1 SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2025-05-22 WO disclosed
WO-2025096300-A1 NOVEL METHODS FOR THE PREPARATION OF 3-AZABICYLCO[3.1,0]HEXANE-6-CARBOXAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2025-05-08 WO disclosed
WO-2025067347-A1 PHAGE PARTICLE COMPLEX, PREPARATION METHOD THEREFOR, AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2025-04-03 WO disclosed
CN-119490464-A Preparation method of 1,2, 3-triazole compound and application thereof in antifungal field 中国人民解放军海军军医大学 2025-02-21 CN disclosed
CN-114206904-B Selective BCRP/ABCG2 transporter inhibitors as agents for eliminating resistance to anticancer agents 格勒诺布尔-阿尔卑斯大学 2024-12-03 CN disclosed
US-20240295548-A1 PHOTOAFFINITY PROBES PROMEGA CORPORATION 2024-09-05 US disclosed
WO-1995014653-A1 METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-06-01 WO disclosed
EP-0641333-A1 METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS. SEARLE & CO (US) 1995-03-08 EP disclosed
EP-0593557-A1 AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY. MERCK SHARP & DOHME (GB) 1994-04-27 EP disclosed
WO-1993023388-A1 METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1993-11-25 WO disclosed
US-5254683-A Neurological disorders IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-10-19 US disclosed
WO-1993001160-A1 AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY MERCK SHARP & DOHME LIMITED (GB) 1993-01-21 WO disclosed
EP-0522808-A2 Aromatic compounds, pharmaceutical compositions containing them and their use in therapy MERCK SHARP & DOHME LTD. (GB) 1993-01-13 EP disclosed
EP-0517876-A1 THERAPEUTIC BENZAZEPINE COMPOUNDS. ICI PLC (GB) 1992-12-16 EP disclosed
WO-1992011854-A1 THERAPEUTIC BENZAZEPINE COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263392-A1 AMINOBENZAZEPINE COMPOUNDS, IMMUNOCONJUGATES, AND USES THEREOF IDO2, IDO1, BCR IDO1 2/4885TSHR 3812/4885TRPA1 3799/4885
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BCL6, CLTB, MET IDO1 3561/4885TSHR 1278/4885TRPA1 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.