Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.44 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ICMT | O60725 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28730799 | 1.00 | KDM5A (0.49) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL3069416 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL2421781 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL8991567 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL8991563 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL28829383 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL28069559 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL29702498 | 0.93 | DNM1 (0.46) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL7196007 | 0.91 | KDM5A (0.49) | KDM5APHF8KDM4CCA1CA2 | |
| Sulfuric Acid SCHEMBL7196009 | 0.91 | KDM5A (0.49) | KDM5APHF8KDM4CCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849841-B1 | Phase Change Ink Additives | XEROX CORP (US) | 2009-06-17 | — | — | EP | claimed |
| US-20070252879-A1 | PHASE CHANGE INK ADDITIVES | XEROX CORPORATION (US) | 2007-11-01 | — | — | US | claimed |
| EP-1849841-B1 | Phase Change Ink Additives | XEROX CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20070252879-A1 | PHASE CHANGE INK ADDITIVES | XEROX CORPORATION (US) | 2007-11-01 | — | — | US | disclosed |
| EP-1849841-A1 | Phase Change Ink Additives | Xerox Corporation (US) | 2007-10-31 | — | — | EP | disclosed |