Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 7/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622801 | 0.76 | TNKS (0.55) | TNKSTSHRMAPK1HPGDUSP2 | |
| SCHEMBL15289179 | 0.73 | ALDH1A1 (0.56) | TNKSTSHRMAPK1HPGDUSP2 | |
| SCHEMBL16231487 | 0.73 | KDM4E (0.50) | ALDH1A1CHRNB2CHRNA4POLB | |
| SCHEMBL14580062 | 0.72 | TNKS (0.49) | TNKSTSHRMAPK1HPGDUSP2 | |
| SCHEMBL30615432 | 0.71 | AURKA (0.48) | TNKSLMNA | |
| SCHEMBL21464135 | 0.71 | AURKA (0.48) | TNKSLMNA | |
| SCHEMBL16455992 | 0.70 | TNKS (0.50) | TNKSTSHRMAPK1HPGDUSP2 | |
| SCHEMBL16456377 | 0.70 | MAPK1 (0.50) | TNKSTSHRMAPK1HPGDUSP2 | |
| SCHEMBL1269528 | 0.70 | MKNK1 (0.41) | TNKSTSHRMAPK1HPGDUSP2 | |
| SCHEMBL11298609 | 0.69 | MKNK1 (0.48) | TSHRMAPK1HPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078992-A1 | LINEAR TRICYCLIC COMPOUNDS AS P38 KINASE INHIBITORS | AMGEN INC. (US) | 2009-06-25 | — | — | WO | disclosed |