Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.57 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008693 | 0.87 | F10 (0.58) | F10AR | |
| SCHEMBL4463259 | 0.87 | F10 (0.74) | F10AR | |
| SCHEMBL4473851 | 0.87 | F10 (0.61) | F10ARPDE7A | |
| SCHEMBL5905038 | 0.86 | F10 (0.57) | F10ARHDAC8 | |
| SCHEMBL4003085 | 0.86 | F10 (0.78) | F10AR | |
| SCHEMBL4008979 | 0.85 | F10 (0.67) | F10AR | |
| SCHEMBL4005074 | 0.83 | F10 (0.53) | F10ARHDAC8 | |
| SCHEMBL4006744 | 0.83 | F10 (0.57) | F10ARHDAC8 | |
| SCHEMBL4006115 | 0.82 | F10 (0.52) | F10ARHDAC8 | |
| SCHEMBL4472368 | 0.82 | F10 (0.59) | F10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563786-B2 | Substituted thiophenecarboxamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-21 | — | — | US | claimed |
| US-20060069082-A1 | Novel substituted thiophenecarboxamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-03-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069082-A1 | Novel substituted thiophenecarboxamides, their preparation and their use as medicaments | P2RY11, P2RX5, TPMT | F10 2756/4885AR 442/4885PDE7A 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.