Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003085 | 0.93 | F10 (0.78) | F10AR | |
| SCHEMBL4008693 | 0.89 | F10 (0.58) | F10AR | |
| SCHEMBL4003675 | 0.88 | F10 (0.65) | F10ARMITFPAX8CNR2 | |
| SCHEMBL4462935 | 0.88 | F10 (0.71) | F10AR | |
| SCHEMBL4004686 | 0.85 | F10 (0.57) | F10AR | |
| SCHEMBL4006744 | 0.85 | F10 (0.57) | F10AR | |
| SCHEMBL5905038 | 0.85 | F10 (0.57) | F10AR | |
| SCHEMBL4002765 | 0.84 | F10 (0.68) | F10AR | |
| SCHEMBL4002499 | 0.84 | F10 (0.56) | F10AR | |
| SCHEMBL3999949 | 0.83 | F10 (0.69) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563786-B2 | Substituted thiophenecarboxamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-21 | — | — | US | claimed |
| US-20060069082-A1 | Novel substituted thiophenecarboxamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-03-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069082-A1 | Novel substituted thiophenecarboxamides, their preparation and their use as medicaments | P2RY11, P2RX5, TPMT | F10 2756/4885AR 442/4885MITF 1919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.