Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464152 | 0.81 | HDAC4 (0.65) | HSD11B1HDAC4ALDH1A1CCR8 | |
| SCHEMBL25464161 | 0.81 | HDAC4 (0.65) | HSD11B1HDAC4ALDH1A1CCR8 | |
| SCHEMBL4003536 | 0.81 | ALDH1A1 (0.64) | HSD11B1ALDH1A1CCR8 | |
| SCHEMBL4003532 | 0.81 | ALDH1A1 (0.64) | HSD11B1ALDH1A1CCR8 | |
| SCHEMBL25464591 | 0.80 | HDAC4 (0.67) | HSD11B1HDAC4ALDH1A1CCR8 | |
| SCHEMBL31045867 | 0.80 | USP30 (0.51) | HSD11B1HDAC4 | |
| SCHEMBL31045909 | 0.80 | USP30 (0.51) | HSD11B1HDAC4 | |
| SCHEMBL4961970 | 0.79 | POLB (0.57) | HSD11B1HDAC4ALDH1A1 | |
| SCHEMBL31045653 | 0.78 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL31045697 | 0.77 | USP30 (0.54) | HSD11B1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20060122197-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2006-06-08 | — | — | US | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122197-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | HSD11B1 1/4885HDAC4 1630/4885ALDH1A1 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.