Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 4/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23235688 | 0.84 | HCAR2 (0.47) | RBP4MEN1KMT2A | |
| SCHEMBL15286661 | 0.84 | MEN1 (0.43) | RBP4HSD11B1MEN1KMT2A | |
| SCHEMBL6218871 | 0.80 | RBP4 (0.40) | RBP4HSD11B1MEN1KMT2A | |
| SCHEMBL2527420 | 0.80 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL17397770 | 0.80 | MEN1 (0.40) | RBP4MEN1KMT2A | |
| SCHEMBL2642390 | 0.80 | PDK2 (0.46) | — | |
| SCHEMBL4006919 | 0.80 | GPR119 (0.57) | — | |
| SCHEMBL20473475 | 0.80 | CHRM4 (0.47) | HSD11B1 | |
| SCHEMBL13770265 | 0.80 | PDK2 (0.39) | — | |
| SCHEMBL3319287 | 0.78 | HCAR2 (0.46) | RBP4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |