Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010973 | 0.86 | ENPP2 (0.41) | PTGDR2MAPTHPGDENPP2TAAR1 | |
| SCHEMBL4012388 | 0.85 | PTGDR2 (0.38) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL4005110 | 0.81 | HPGD (0.43) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL4013090 | 0.81 | TAAR1 (0.39) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL4006857 | 0.80 | HPGD (0.41) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL4012751 | 0.80 | PTGDR2 (0.40) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL13963196 | 0.79 | HPGD (0.37) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL13963194 | 0.78 | PTGDR2 (0.43) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL4008415 | 0.78 | MAPT (0.41) | PTGDR2MAPTHPGDHTTNPSR1 | |
| SCHEMBL4010032 | 0.78 | PRLHR (0.38) | PTGDR2MAPTHPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |