Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004746 | 0.86 | PTGDR2 (0.45) | ENPP2TAAR1PTGDR2HPGDCHRM1 | |
| SCHEMBL13962989 | 0.84 | ENPP2 (0.36) | ENPP2TAAR1PTGDR2MAPK1HPGD | |
| SCHEMBL4012387 | 0.83 | ENPP2 (0.35) | ENPP2TAAR1PTGDR2MAPK1 | |
| SCHEMBL4009380 | 0.80 | HPGD (0.39) | ENPP2TAAR1PTGDR2MAPK1HPGD | |
| SCHEMBL5708738 | 0.80 | PTGDR2 (0.44) | ENPP2TAAR1PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL13963129 | 0.78 | TAAR1 (0.36) | ENPP2TAAR1PTGDR2MAPK1HPGD | |
| SCHEMBL4009901 | 0.78 | CHRM1 (0.38) | ENPP2TAAR1PTGDR2CHRM1 | |
| SCHEMBL13963199 | 0.77 | HPGD (0.39) | ENPP2TAAR1PTGDR2MAPK1HPGD | |
| SCHEMBL4002037 | 0.77 | HPGD (0.39) | TAAR1PTGDR2MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL13962552 | 0.76 | PTGDR2 (0.36) | ENPP2TAAR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |