SCHEMBL4005041

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4010456	0.85	DRD2 (0.53)	DRD4DRD2DRD3KDM4EALDH1A1
	SCHEMBL4010683	0.84	DRD4 (1.00)	DRD4DRD2DRD3KDM4EALDH1A1
	SCHEMBL4001572	0.83	DRD2 (1.00)	DRD4DRD2DRD3KDM4EALDH1A1
	Pd-168,077 SCHEMBL4002275	0.81	DRD4 (1.00)	DRD4DRD2DRD3KDM4EALDH1A1
	Pd-168,077 SCHEMBL29435417	0.81	DRD4 (1.00)	DRD4DRD2DRD3KDM4EALDH1A1
	SCHEMBL4006700	0.80	DRD2 (0.53)	DRD4DRD2DRD3KDM4EALDH1A1
	SCHEMBL4002664	0.76	DRD2 (1.00)	DRD4DRD2DRD3KDM4EALDH1A1
	Pd-168,077 SCHEMBL30730667	0.76	KDM4E (1.00)	DRD4DRD2DRD3KDM4EALDH1A1
	SCHEMBL5739562	0.75	DRD4 (0.49)	DRD4DRD2DRD3KDM4EALDH1A1
	SCHEMBL27597061	0.73	DRD4 (0.59)	DRD4DRD2DRD3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.