SCHEMBL4006071

SCHEMBL4006071

[CH2]N(C[Si](OCC)(OCC)OCC)C1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 2/20 0.32
ADH1C P00326 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4003379 0.84 ADH1A (0.32) ADH1AADH1C
SCHEMBL4004130 0.81 ADH1A (0.34) ADH1AADH1CALDH1A1
SCHEMBL2927045 0.81 ADH1A (0.34) ADH1AADH1CALDH1A1
SCHEMBL4344034 0.79 HRH4 (0.37) ADH1AADH1CALDH1A1
SCHEMBL15360878 0.76 ADH1A (0.32) ADH1AADH1C
SCHEMBL18138426 0.74 ALDH1A1 (0.34) ADH1AADH1CALDH1A1
SCHEMBL15360350 0.73
SCHEMBL15360922 0.71
SCHEMBL6977261 0.71 ADH1A (0.46) ADH1AADH1CALDH1A1
SCHEMBL28779553 0.70 HRH4 (0.33) ADH1AADH1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229920-A1 HIGH-PERFORMANCE COSMETIC PRODUCTS CONTAINING A POLYORGANOSILOXANE AND A DIPEPTIDE Evonik Degussa GmbH (DE) 2017-10-18 EP claimed
WO-2016091781-A1 HIGH-PERFORMANCE COSMETIC PRODUCTS CONTAINING A POLYORGANOSILOXANE AND A DIPEPTIDE EVONIK DEGUSSA GMBH (DE) 2016-06-16 WO claimed
US-20220142905-A1 COSMETIC PRODUCT CONTAINING A MIXTURE OF SILICONES HENKEL AG & CO. KGAA (DE) 2022-05-12 US disclosed
EP-3937889-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND AND A MIXTURE OF SILICONES Henkel AG & Co. KGaA (DE) 2022-01-19 EP disclosed
EP-3937891-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND, A FILM-FORMING POLYMER AND A MIXTURE OF SILICONES Henkel AG & Co. KGaA (DE) 2022-01-19 EP disclosed
US-11213476-B2 Method for gentle, chemical hair treatment HENKEL AG & CO. KGAA (DE) 2022-01-04 US disclosed
WO-2020182474-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND AND A MIXTURE OF SILICONES HENKEL AG & CO. KGAA (DE) 2020-09-17 WO disclosed
WO-2020182476-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND, A FILM-FORMING POLYMER AND A MIXTURE OF SILICONES HENKEL AG & CO. KGAA (DE) 2020-09-17 WO disclosed
US-20200138694-A1 METHOD FOR GENTLE, CHEMICAL HAIR TREATMENT HENKEL AG & CO. KGAA (DE) 2020-05-07 US disclosed
EP-3233199-B1 METHOD FOR MAINTAINING THE COLOUR OF DYED AND/OR HIGHLIGHTED KERATIN FIBRES HENKEL AG & CO KGAA (DE) 2019-02-06 EP disclosed
US-10137068-B2 Method for maintaining the color of dyed and/or highlighted keratin fibres HENKEL AG & CO. KGAA (DE) 2018-11-27 US disclosed
EP-1721926-B1 Process for the production of dispersions of cross linked organopolysiloxanes WACKER CHEMIE AG (DE) 2009-07-01 EP disclosed
EP-1921203-B1 Treatment of fiberfill fibers with aqueous dispersions of organopolysiloxanes WACKER CHEMIE AG (DE) 2009-06-17 EP disclosed
EP-1921203-A1 Treatment of fiberfill fibers with aqueous dispersions of organopolysiloxanes Wacker Chemie AG (DE) 2008-05-14 EP disclosed
EP-1921106-A1 Preparation of aqueous dispersions of organopolysiloxanes Wacker Chemie AG (DE) 2008-05-14 EP disclosed
US-20080107815-A1 Preparation Of Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
US-20080107814-A1 Treatment Of Fiberfill Fibers With Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
US-20080064813-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2008-03-13 US disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10137068-B2 Method for maintaining the color of dyed and/or highlighted keratin fibres KRT18, KLK5, KLK7 ADH1A 863/4885ADH1C 874/4885ALDH1A1 1607/4885
US-20200138694-A1 METHOD FOR GENTLE, CHEMICAL HAIR TREATMENT KRT18, POLR1C, TUBA1C ADH1A 300/4885ADH1C 359/4885ALDH1A1 297/4885
US-11213476-B2 Method for gentle, chemical hair treatment KRT18, POLR1C, TUBA1C ADH1A 300/4885ADH1C 359/4885ALDH1A1 297/4885
US-20220142905-A1 COSMETIC PRODUCT CONTAINING A MIXTURE OF SILICONES SQLE, LIPA, HSD17B4 ADH1A 12/4885ADH1C 71/4885ALDH1A1 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.