Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019341 | 0.83 | NPC1 (0.52) | SMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL4001461 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL3996305 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AEGLN1ALDH1A1MAPT | |
| SCHEMBL4006319 | 0.80 | EGLN1 (0.58) | SMN1; SMN2MEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL4132392 | 0.72 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6169172 | 0.71 | MEN1 (0.83) | SMN1; SMN2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11306557 | 0.69 | HPGD (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8692725 | 0.68 | BRD4 (0.58) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31324947 | 0.67 | KDM4E (0.74) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL13936057 | 0.67 | KDM4E (0.74) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090171084-A1 | PRODUCTION METHOD OF AMINOPYRIMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2009-07-02 | — | — | US | claimed |
| US-7491822-B2 | Production method of aminopyrimidine compound | AJINOMOTO CO., INC. (JP) | 2009-02-17 | — | — | US | claimed |
| US-20050215789-A1 | Production method of aminopyrimidine compound | AJINOMOTO CO., INC. (JP) | 2005-09-29 | — | — | US | claimed |
| EP-1577304-A1 | Production method of aminopyrimidine compound | Ajinomoto Co., Inc. (JP) | 2005-09-21 | — | — | EP | claimed |
| US-20090171084-A1 | PRODUCTION METHOD OF AMINOPYRIMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2009-07-02 | — | — | US | disclosed |
| US-7491822-B2 | Production method of aminopyrimidine compound | AJINOMOTO CO., INC. (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | AJINOMOTO CO. INC (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009003-A1 | Production method of diaminopyrimidine compounds | Ajinomoto Co., Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20050215789-A1 | Production method of aminopyrimidine compound | AJINOMOTO CO., INC. (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1577304-A1 | Production method of aminopyrimidine compound | Ajinomoto Co., Inc. (JP) | 2005-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | DPYD, DHPS, UMPS | SMN1; SMN2 2471/4885MEN1 2530/4885KMT2A 1803/4885 |
| US-20050215789-A1 | Production method of aminopyrimidine compound | AZI2, DPYD, DHPS | SMN1; SMN2 1648/4885MEN1 177/4885KMT2A 1519/4885 |
| US-20090171084-A1 | PRODUCTION METHOD OF AMINOPYRIMIDINE COMPOUND | AZI2, DPYD, DHPS | SMN1; SMN2 1648/4885MEN1 177/4885KMT2A 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.