Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132347 | 0.80 | CCNE1 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4144040 | 0.80 | LMNA (0.54) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4132365 | 0.80 | CCNE1 (0.49) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4006345 | 0.72 | SMN1; SMN2 (0.54) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6169172 | 0.71 | MEN1 (0.83) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13530881 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL23331269 | 0.70 | MEN1 (0.64) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL20596981 | 0.70 | L3MBTL1 (0.64) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL30116211 | 0.70 | L3MBTL1 (0.64) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL24978697 | 0.70 | CSNK1D (0.49) | MEN1KMT2APOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | AJINOMOTO CO. INC (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009003-A1 | Production method of diaminopyrimidine compounds | Ajinomoto Co., Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | DPYD, DHPS, UMPS | MEN1 2530/4885KMT2A 1803/4885POLB 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.