Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714050 | 0.88 | GSTP1 (0.41) | GLALMNAALDH1A1ESR1PGR | |
| SCHEMBL7179832 | 0.87 | GLA (0.30) | GLALMNA | |
| SCHEMBL616033 | 0.86 | GSTP1 (0.42) | GLAALDH1A1ESR1PGRCHRM2 | |
| SCHEMBL9815308 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11545012 | 0.73 | — | — | |
| SCHEMBL2533106 | 0.73 | LMNA (0.38) | GLALMNAALDH1A1ESR1PGR | |
| SCHEMBL25113 | 0.73 | — | — | |
| SCHEMBL11929861 | 0.72 | LMNA (0.39) | GLALMNAALDH1A1ESR1PGR | |
| Methyl Alcohol SCHEMBL11662062 | 0.71 | LMNA (0.37) | GLALMNAALDH1A1ESR1PGR | |
| Formaldehyde SCHEMBL18112525 | 0.70 | LMNA (0.35) | GLALMNAALDH1A1ESR1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63049099-A | — | — | None | — | — | JP | disclosed |
| WO-2009076397-A2 | ANTIVIRAL ACTIVITY OF CYCLOPENTENE NITRO-ESTER AND DERIVATIVES | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-06-18 | — | — | WO | disclosed |
| EP-0272202-B1 | Process for the preparation of optically active bicyclo[3.3.0]octanedione-carboxylic-acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-5093250-A | Process for producing optically active bicyclo[3.3.0]octanedione carboxylic acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| EP-0272202-A1 | Process for the preparation of optically active bicyclo[3.3.0]octanedione-carboxylic-acid esters | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988003569-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BICYCLO[3.3.0]OCTANDIONE CARBOXYLIC ACID ESTERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-05-19 | — | — | WO | disclosed |
| JP-S6349099-A | PRODUCTION OF OPTICALLY ACTIVE 3-CHLORO-4-HYDROXY-2-CYCLOPENTENONE | FUJI YAKUHIN KOGYO KK | 1988-03-01 | — | — | JP | disclosed |