Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666390 | 0.83 | ADRA2C (0.36) | KMT2A | |
| SCHEMBL1801253 | 0.72 | CCR5 (0.36) | — | |
| SCHEMBL12791101 | 0.57 | KMT2A (0.76) | KMT2A | |
| SCHEMBL12791027 | 0.56 | KMT2A (0.38) | KMT2A | |
| SCHEMBL12791190 | 0.56 | KMT2A (0.34) | KMT2A | |
| SCHEMBL12790998 | 0.56 | KMT2A (0.47) | KMT2A | |
| SCHEMBL18390390 | 0.55 | CYP1A2 (0.38) | — | |
| SCHEMBL3971878 | 0.53 | CXCR4 (0.56) | KMT2A | |
| SCHEMBL8252575 | 0.52 | ALDH1A1 (0.41) | KMT2A | |
| SCHEMBL25931529 | 0.52 | CYP1A2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095402-A9 | SUBSTITUTED 1,4,8-TRIAZASPIRO[4.5]DECAN-2-ON COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | GRUENENTHAL GMBH (DE) | 2009-06-11 | — | — | WO | disclosed |