Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008900 | 0.81 | LMNA (0.48) | LMNAKMT2ADHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL13240376 | 0.81 | HDAC3 (0.43) | LMNAKMT2ASMN1; SMN2RAB9AHTT | |
| SCHEMBL13299640 | 0.80 | MEN1 (0.47) | LMNAKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4007127 | 0.79 | DPEP1 (0.39) | LMNAKMT2ARAB9AMAPTNPSR1 | |
| SCHEMBL13299639 | 0.78 | SMN1; SMN2 (0.40) | LMNAKMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10996472 | 0.78 | KMT2A (0.46) | LMNAKMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL10996467 | 0.78 | KMT2A (0.46) | LMNAKMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8038684 | 0.76 | NAMPT (0.60) | LMNAKMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1996947 | 0.75 | AKR1C3 (0.51) | LMNAKMT2ADHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL11779413 | 0.73 | LMNA (0.46) | LMNAKMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074409-A1 | S-TRIAZINE COMPOUNDS CONTAINING ONE AMINOSILOXANE GROUP AND TWO PARTICULAR PARA-AMINOBENZALMALONATE GROUPS; COSMETIC COMPOSITIONS CONTAINING SAID DERIVATIVES; USES OF SAID S-TRIAZINE DERIVATIVES | L'OREAL (FR) | 2009-06-18 | — | — | WO | disclosed |