Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240377 | 0.82 | CDK2 (0.46) | — | |
| SCHEMBL13299447 | 0.82 | MEN1 (0.55) | LMNAKMT2ARAB9AEPHX2NPC1 | |
| SCHEMBL4007541 | 0.81 | LMNA (0.51) | LMNAKMT2AALDH1A1DHODHKDM4E | |
| SCHEMBL4004783 | 0.81 | DPEP1 (0.45) | LMNAKMT2AMAPTNPSR1MEN1 | |
| SCHEMBL14505302 | 0.74 | CDK2 (0.40) | — | |
| SCHEMBL8038684 | 0.73 | NAMPT (0.60) | LMNAKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5146048 | 0.70 | DHODH (0.54) | KMT2AALDH1A1DHODHKDM4ESMN1; SMN2 | |
| SCHEMBL4871556 | 0.69 | PTGS2 (0.56) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| Cyclohexylamine SCHEMBL7801657 | 0.67 | KDM4E (0.52) | LMNAKMT2AALDH1A1DHODHKDM4E | |
| SCHEMBL17342576 | 0.67 | MGLL (0.54) | LMNAKMT2AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074409-A1 | S-TRIAZINE COMPOUNDS CONTAINING ONE AMINOSILOXANE GROUP AND TWO PARTICULAR PARA-AMINOBENZALMALONATE GROUPS; COSMETIC COMPOSITIONS CONTAINING SAID DERIVATIVES; USES OF SAID S-TRIAZINE DERIVATIVES | L'OREAL (FR) | 2009-06-18 | — | — | WO | disclosed |