Biphenyl

Biphenyl

SCHEMBL4007752

c1ccc(-c2cccc(-c3cccc4ccccc34)c2-c2cccc3ccccc23)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
MAPK1 P28482 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
ATM Q13315 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TNF P01375 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9481417 0.98 MAPT (0.47) MAPTCA12CA1CA2CA9
SCHEMBL30332655 0.92 MAPT (0.46) MAPTCA12CA1CA2CA9
SCHEMBL25240721 0.91 HPRT1 (0.50) MAPTCA12CA1CA2CA9
SCHEMBL30332975 0.90 MAPT (0.45) MAPTCA12CA1CA2CA9
SCHEMBL399398 0.90 MAPT (0.47) MAPTCA12CA1CA2CA9
SCHEMBL25403876 0.89 HPRT1 (0.52) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL4010018 0.89 KDM4E (0.44) MAPTCA12CA1CA2CA9
SCHEMBL28594179 0.89 MAPT (0.44) MAPTCA12CA1CA2CA9
Biphenyl SCHEMBL1073325 0.87 ALDH1A1 (0.55) MAPTCA12CA1CA2CA9
SCHEMBL8107861 0.87 DHFR (0.48) KDM4EALDH1A1HPGDTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009082157-A2 ARYL AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DOOSAN CORPORATION (KR) 2009-07-02 WO disclosed