Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30332655 | 0.96 | MAPT (0.46) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL28594179 | 0.93 | MAPT (0.44) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL399398 | 0.90 | MAPT (0.47) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL9481417 | 0.90 | MAPT (0.47) | KDM4EALDH1A1MAPTHPGDTP53 | |
| Biphenyl SCHEMBL4007752 | 0.89 | MAPT (0.46) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL18260187 | 0.85 | DNMT1 (0.48) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL30006027 | 0.85 | DNMT1 (0.48) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL28223683 | 0.84 | DHFR (0.43) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL5778909 | 0.84 | DHFR (0.46) | KDM4EALDH1A1MAPTHPGDTP53 | |
| SCHEMBL25240721 | 0.84 | HPRT1 (0.50) | KDM4EALDH1A1MAPTHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082157-A2 | ARYL AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | DOOSAN CORPORATION (KR) | 2009-07-02 | — | — | WO | disclosed |