Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051944 | 1.00 | PDE1B (0.39) | PDE1BALDH1A1HPGDUSP1KDM4E | |
| SCHEMBL4056161 | 0.87 | PDE1B (0.39) | PDE1BALDH1A1HPGDUSP1KDM4E | |
| SCHEMBL4056155 | 0.87 | PDE1B (0.39) | PDE1BALDH1A1HPGDUSP1KDM4E | |
| SCHEMBL4054540 | 0.83 | PDE1B (0.39) | PDE1BALDH1A1HPGDKDM4EKDM4A | |
| SCHEMBL4048837 | 0.80 | PDE1B (0.42) | PDE1BALDH1A1HPGDKDM4EKDM4A | |
| SCHEMBL4057925 | 0.79 | ADORA3 (0.39) | PDE1BALDH1A1HPGDKDM4EKDM4A | |
| Hydrochloric Acid SCHEMBL4053239 | 0.74 | KIF11 (0.65) | — | |
| SCHEMBL4056075 | 0.73 | KIF11 (0.40) | PDE1BNPSR1L3MBTL1TLR7 | |
| SCHEMBL4049144 | 0.72 | KIF11 (0.66) | — | |
| SCHEMBL4049146 | 0.72 | KIF11 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074677-A2 | PYRAZOLOTRIAZINES | 4SC AG (DE) | 2009-06-18 | — | — | WO | disclosed |
| EP-2070932-A1 | Pyrazolotriazines | 4SC AG (DE) | 2009-06-17 | — | — | EP | disclosed |