Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696323 | 0.81 | SMN1; SMN2 (0.38) | FFAR1MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL696569 | 0.79 | PPARG (0.41) | FFAR1PPARGPPARAPPARDPTGES | |
| SCHEMBL695992 | 0.79 | CYP1A2 (0.39) | FFAR1MAPTSMN1; SMN2 | |
| SCHEMBL698246 | 0.78 | MAPT (0.44) | FFAR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3533515 | 0.78 | TP53 (0.40) | FFAR1MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL696627 | 0.76 | GRIN2B (0.40) | FFAR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4014276 | 0.75 | SMN1; SMN2 (0.51) | FFAR1SMN1; SMN2TP53 | |
| SCHEMBL696322 | 0.75 | ALDH1A1 (0.38) | MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL697760 | 0.75 | L3MBTL1 (0.38) | FFAR1MAPTLMNA | |
| SCHEMBL699098 | 0.75 | FFAR1 (0.41) | FFAR1PPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |