Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014297 | 0.87 | FAAH (0.76) | FAAH | |
| SCHEMBL3936249 | 0.87 | FAAH (0.72) | FAAHALPLMKNK1 | |
| SCHEMBL3934225 | 0.87 | FAAH (0.72) | FAAHALPLMKNK1 | |
| SCHEMBL4018033 | 0.86 | FAAH (0.65) | FAAHEPHX2CNR2ALPL | |
| SCHEMBL4018971 | 0.85 | FAAH (0.76) | FAAH | |
| SCHEMBL3934462 | 0.85 | FAAH (0.72) | FAAHEPHX2CNR2ALPLMKNK1 | |
| SCHEMBL3932111 | 0.85 | FAAH (0.75) | FAAHMKNK1 | |
| SCHEMBL3939171 | 0.85 | FAAH (0.77) | FAAHEPHX2ALPL | |
| SCHEMBL3942409 | 0.85 | FAAH (0.77) | FAAHALPLMKNK1 | |
| SCHEMBL3942824 | 0.84 | FAAH (0.71) | FAAHEPHX2CNR2ALPLMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |