Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | CTSA | P10619 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014276 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2FFAR1ESR1KMT2AFPR2 | |
| SCHEMBL4007502 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2FFAR1ESR1KMT2AFPR2 | |
| SCHEMBL4009094 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ESR1KMT2AFPR2ALDH1A1 | |
| SCHEMBL697680 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ESR1KMT2AFPR2ALDH1A1 | |
| SCHEMBL698417 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ESR1KMT2AFPR2ALDH1A1 | |
| SCHEMBL1573152 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ESR1KMT2AFPR2ALDH1A1 | |
| SCHEMBL1573428 | 0.79 | APAF1 (0.42) | SMN1; SMN2KMT2AFPR2ALDH1A1MAPT | |
| SCHEMBL696323 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2FFAR1KMT2AFPR2ALDH1A1 | |
| SCHEMBL698793 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1MAPT | |
| SCHEMBL698574 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |