Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070962 | 0.91 | L3MBTL1 (0.57) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL7199868 | 0.90 | L3MBTL1 (0.56) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL9215275 | 0.88 | L3MBTL1 (0.55) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL3250233 | 0.85 | L3MBTL1 (0.54) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL10458221 | 0.84 | L3MBTL1 (0.60) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL6573378 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL2091560 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL3524104 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL72484 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KDM4EMAOBAOC3ALOX15 | |
| SCHEMBL9721587 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KDM4EMAOBAOC3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233077-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12428373-B2 | Dopamine D2 receptor ligands | THE BROAD INSTITUTE, INC. (US) | 2025-09-30 | — | — | US | disclosed |
| CN-118164914-A | Indazole compound and synthetic method and application thereof | 华东师范大学 | 2024-06-11 | — | — | CN | disclosed |
| US-20230143552-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230143552-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230143552-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11498896-B2 | Dopamine D2 receptor ligands | THE BROAD INSTITUTE, INC. (US) | 2022-11-15 | — | — | US | disclosed |
| CN-114262301-A | Small molecule antagonist targeting EP4 receptor and application thereof in osteoarthritis and cartilage defect treatment | 华东师范大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-108929281-B | Triazole compound and synthesis method and application thereof | 华东师范大学 | 2021-12-24 | — | — | CN | disclosed |
| US-20210147355-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| EP-0347925-B1 | Fungicidal heterocyclic nitrogen compounds | MINI RICERCA SCIENT TECNOLOG (IT) | 1993-11-18 | — | — | EP | disclosed |
| EP-0532127-A1 | Oximic derivatives with fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-03-17 | — | — | EP | disclosed |
| US-5051440-A | Imidazole derivatives as fungicides on plants | PRESIDENZA DEL CONSIGLIO DEI MINISTRI (IT) | 1991-09-24 | — | — | US | disclosed |
| EP-0347925-A1 | Fungicidal heterocyclic nitrogen compounds | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1989-12-27 | — | — | EP | disclosed |
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| EP-0017209-B1 | SUBSTITUTED ALKYLAMMONIUM SALTS, THEIR PREPARATION AND USE IN PLANT GROWTH REGULATION | BASF Aktiengesellschaft (DE) | 1982-12-22 | — | — | EP | disclosed |
| US-4350518-A | Plant growth regulating substituted alkylammonium salts | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| US-4249938-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |
| EP-0017209-A1 | Substituted alkylammonium salts, their preparation and use in plant growth regulation | BASF Aktiengesellschaft (DE) | 1980-10-15 | — | — | EP | disclosed |
| US-4027028-A | HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11498896-B2 | Dopamine D2 receptor ligands | DRD2, SLC6A3, NTSR2 | L3MBTL1 1719/4885KDM4E 4204/4885MAOB 331/4885 |
| US-20230143552-A1 | DOPAMINE D2 RECEPTOR LIGANDS | DRD2, SLC6A3, NTSR2 | L3MBTL1 1719/4885KDM4E 4204/4885MAOB 331/4885 |
| US-20210147355-A1 | DOPAMINE D2 RECEPTOR LIGANDS | DRD2, SLC6A3, NTSR2 | L3MBTL1 1719/4885KDM4E 4204/4885MAOB 331/4885 |
| US-12428373-B2 | Dopamine D2 receptor ligands | DRD2, SLC6A3, NTSR2 | L3MBTL1 1719/4885KDM4E 4204/4885MAOB 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.