Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608511 | 0.78 | MAPT (0.35) | KDM4ERAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6422107 | 0.74 | ERN1 (0.39) | KCNQ3KCNQ2KDM4ERAB9AALDH1A1 | |
| SCHEMBL3610666 | 0.73 | MAPT (0.37) | KDM4ERAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL4582844 | 0.68 | HSD11B1 (0.41) | KDM4ERAB9ASMN1; SMN2ALDH1A1GABRG2 | |
| SCHEMBL3618362 | 0.68 | KDM4E (0.36) | KDM4ERAB9ASMN1; SMN2ALDH1A1GABRG2 | |
| SCHEMBL21503917 | 0.66 | MAPT (0.43) | KDM4ERAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL3618629 | 0.66 | RPS6KB2 (0.36) | KDM4ERAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL3611240 | 0.65 | NPC1 (0.38) | KDM4ERAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL2455815 | 0.65 | ALDH1A1 (0.41) | KDM4ERAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6744117 | 0.64 | MAPT (0.44) | KDM4ERAB9AALDH1A1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041113-A1 | NOVEL PYRIDAZINE DERIVATIVES | Syngeta Participations AG (CH) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008009406-A1 | NOVEL PYRIDAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-24 | — | — | WO | disclosed |