Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720380 | 0.89 | EPHX2 (1.00) | EPHX2GAA | |
| SCHEMBL4111205 | 0.85 | EPHX2 (0.77) | EPHX2GAAMAPTSMN1; SMN2 | |
| SCHEMBL3956569 | 0.79 | EPHX2 (0.67) | EPHX2GAAMAPTSMN1; SMN2 | |
| SCHEMBL4012369 | 0.79 | EPHX2 (0.69) | EPHX2GAA | |
| SCHEMBL4013955 | 0.79 | EPHX2 (0.70) | EPHX2MAPTSMN1; SMN2 | |
| SCHEMBL14077968 | 0.78 | EPHX2 (0.70) | EPHX2GAAMAPTSMN1; SMN2 | |
| SCHEMBL4015336 | 0.77 | EPHX2 (0.80) | EPHX2 | |
| SCHEMBL3961426 | 0.77 | EPHX2 (0.69) | EPHX2GAA | |
| SCHEMBL4193206 | 0.76 | EPHX2 (0.80) | EPHX2 | |
| SCHEMBL4010411 | 0.76 | EPHX2 (0.67) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | claimed |
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |