Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 18/20 | 0.80 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.65 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719122 | 0.89 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL4123175 | 0.85 | EPHX2 (0.77) | EPHX2EPHX1CXCR3 | |
| SCHEMBL4193206 | 0.83 | EPHX2 (0.80) | EPHX2EPHX1 | |
| SCHEMBL4010411 | 0.82 | EPHX2 (0.67) | EPHX2 | |
| SCHEMBL2752560 | 0.80 | EPHX1 (0.97) | EPHX2EPHX1 | |
| SCHEMBL4132566 | 0.80 | CA12 (0.71) | EPHX2EPHX1CXCR3 | |
| SCHEMBL4010106 | 0.79 | EPHX2 (0.69) | EPHX2EPHX1CXCR3 | |
| SCHEMBL12196149 | 0.79 | EPHX1 (1.00) | EPHX2EPHX1 | |
| SCHEMBL1911203 | 0.78 | EPHX2 (0.67) | EPHX2EPHX1CXCR3 | |
| SCHEMBL357891 | 0.78 | EPHX2 (0.67) | EPHX2EPHX1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | claimed |
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |