Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.82 |
| ▸ | AKR1C3 | P42330 | 10/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010751 | 0.92 | FAAH (0.85) | FAAHAKR1C3AKR1C1AKR1C2 | |
| SCHEMBL3941135 | 0.91 | FAAH (1.00) | FAAHAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL4016630 | 0.91 | FAAH (0.75) | FAAHAKR1C3AKR1C1AKR1C2 | |
| SCHEMBL4017386 | 0.90 | FAAH (0.73) | FAAHAKR1C3AKR1C1AKR1C2 | |
| SCHEMBL3934243 | 0.87 | FAAH (0.83) | FAAHAKR1C3MEN1KMT2A | |
| SCHEMBL3939389 | 0.87 | FAAH (0.83) | FAAHAKR1C3MEN1KMT2A | |
| SCHEMBL3932908 | 0.87 | FAAH (0.83) | FAAHAKR1C3MEN1KMT2A | |
| SCHEMBL3939612 | 0.87 | FAAH (0.83) | FAAHAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL3942978 | 0.87 | FAAH (0.86) | FAAH | |
| SCHEMBL4015887 | 0.86 | FAAH (0.76) | FAAHAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |