SCHEMBL4015887 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	FAAH	O00519	11/20	0.76

▸	KDM4E	B2RXH2	1/20	0.40

▸	GAA	P10253	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	EPHX2	P34913	1/20	0.39

▸	AKR1C3	P42330	1/20	0.39

▸	CTDSP1	Q9GZU7	1/20	0.39

▸	TDP1	Q9NUW8	1/20	0.39

▸	L3MBTL1	Q9Y468	1/20	0.39

▸	MAPT	P10636	1/20	0.39

▸	POLB	P06746	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4018971	0.91	FAAH (0.76)	FAAHMAPT
SCHEMBL4014297	0.91	FAAH (0.76)	FAAHKDM4ETSHRAKR1C3CTDSP1
SCHEMBL4017908	0.90	FAAH (0.72)	FAAHAKR1C3MAPT
SCHEMBL3932388	0.88	FAAH (0.77)	FAAHKDM4EMAPTPOLB
SCHEMBL4010751	0.88	FAAH (0.85)	FAAHAKR1C3
SCHEMBL3941343	0.87	FAAH (0.86)	FAAHKDM4EGAAEPHX2MAPT
SCHEMBL3942978	0.87	FAAH (0.86)	FAAHGAATSHR
SCHEMBL3941135	0.87	FAAH (1.00)	FAAHAKR1C3
SCHEMBL4009971	0.86	FAAH (0.82)	FAAHAKR1C3
SCHEMBL3940445	0.86	FAAH (0.84)	FAAHKDM4EGAAEPHX2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009011904-A1	COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF	RENOVIS, INC. (US)	2009-01-22	—	—	WO	disclosed