Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468266 | 0.84 | NAAA (0.54) | NAAANPC1LMNANFKB1NFKB2 | |
| SCHEMBL4433083 | 0.84 | CES2 (0.50) | NAAANPC1HDAC1GAACNR2 | |
| SCHEMBL28199079 | 0.84 | CES2 (0.50) | NAAANPC1HDAC1GAACNR2 | |
| SCHEMBL8390583 | 0.83 | HSD17B3 (0.54) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1545820 | 0.82 | HPGD (0.49) | NAAANPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL1130569 | 0.81 | HSD17B3 (0.53) | LMNASMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27854800 | 0.80 | KDM4E (0.47) | NAAALMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL10441296 | 0.79 | HDAC3 (0.45) | NPC1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL4004765 | 0.77 | NAAA (0.47) | NAAANPC1LMNANFKB1NFKB2 | |
| SCHEMBL4054017 | 0.77 | HPGD (0.54) | NAAAHDAC3HDAC1HDAC2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |