Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.81 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954392 | 0.89 | PTPN1 (1.00) | PTPN1ERN1MAOAMAOBALDH1A1 | |
| SCHEMBL1997539 | 0.89 | PTPN1 (1.00) | PTPN1ERN1MAOAMAOBALDH1A1 | |
| SCHEMBL29951939 | 0.80 | PTPN1 (0.79) | PTPN1ERN1MAOAMAOBALDH1A1 | |
| SCHEMBL4010048 | 0.77 | PTPN1 (0.57) | PTPN1MAOAMAOBALDH1A1CA12 | |
| SCHEMBL1993748 | 0.74 | PTPN1 (0.69) | PTPN1MAOAMAOBALDH1A1PTPN2 | |
| SCHEMBL13978670 | 0.74 | PTPN1 (0.74) | PTPN1MAOAMAOBALDH1A1PTPN2 | |
| SCHEMBL4008145 | 0.73 | MAOB (0.54) | PTPN1MAOAMAOBALDH1A1CA12 | |
| SCHEMBL27700646 | 0.73 | PTPN1 (0.65) | PTPN1MAOAMAOBALDH1A1CA12 | |
| SCHEMBL4013102 | 0.73 | PTPN1 (0.54) | PTPN1MAOAMAOBALDH1A1CA12 | |
| SCHEMBL11508755 | 0.73 | PTPN1 (0.60) | PTPN1MAOAMAOBALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |