Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 1.00 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954392 | 1.00 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBERN1 | |
| SCHEMBL4010077 | 0.89 | PTPN1 (0.81) | PTPN1PTPN2MAOAMAOBERN1 | |
| SCHEMBL29951939 | 0.88 | PTPN1 (0.79) | PTPN1PTPN2MAOAMAOBERN1 | |
| SCHEMBL13978670 | 0.85 | PTPN1 (0.74) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL1993748 | 0.83 | PTPN1 (0.69) | PTPN1PTPN2MAOAMAOBKDM1A | |
| SCHEMBL27700646 | 0.79 | PTPN1 (0.65) | PTPN1MAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL11508755 | 0.75 | PTPN1 (0.60) | PTPN1MAOAMAOBKDM1AALDH1A1 | |
| SCHEMBL23707495 | 0.75 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL12174817 | 0.75 | PTPN1 (0.67) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL5363245 | 0.75 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072228-A1 | SPECTRAL IMAGING OF PHOTOLUMINESCENT MATERIALS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-06-16 | — | — | WO | claimed |
| US-3984441-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-10-05 | — | — | US | claimed |
| EP-4306106-A1 | NITRO-CONTAINING COMPOUNDS, COMPOSITIONS AND USES THEREOF | Universidade de Aveiro (PT) | 2024-01-17 | — | — | EP | disclosed |
| CN-115433200-B | Tetracyclic compound containing chroman-4-one structure, synthesis method and application | 广州大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115433200-A | Tetracyclic compound containing chroman-4-one structure, synthetic method and application | 广州大学 | 2022-12-06 | — | — | CN | disclosed |
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-11-03 | — | — | US | disclosed |
| US-8022063-B2 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-09-20 | — | — | US | disclosed |
| EP-2336113-A1 | CRTH2 Receptor Ligands for Medical Use | 7TM Pharma A/S (DK) | 2011-06-22 | — | — | EP | disclosed |
| US-20090099189-A1 | CRTH2 Receptor Ligands For Medicinal Uses | 7TM PHARMA A/S (DK) | 2009-04-16 | — | — | US | disclosed |
| US-7202265-B2 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| EP-1758579-A1 | CRTH2 RECEPTOR LIGANDS FOR MEDICINAL USES | 7TM Pharma A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005115382-A1 | CRTH2 RECEPTOR LIGANDS FOR MEDICINAL USES | 7TM PHARMA A/S (DK) | 2005-12-08 | — | — | WO | disclosed |
| US-20050197382-A1 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | SUGEN, INC. | 2005-09-08 | — | — | US | disclosed |
| US-6787671-B2 | FOR PRODUCTION OF ALDEHYDES, CARBOXYLIC ACIDS, ESTERS, OR KETONES VIA REACTION OF OSMIUM CATALYST AND PEROXYMONOSULFURIC ACID | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-09-07 | — | — | US | disclosed |
| US-20030149299-A1 | Catalytic osmium-assisted oxidative cleavage of olefins | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-08-07 | — | — | US | disclosed |
| WO-2003060852-A2 | CATALYTIC OSMIUM-ASSISTED OXIDATIVE CLEAVAGE OF OLEFINS | MICHIGAN STATE UNIVERSITY (US) | 2003-07-24 | — | — | WO | disclosed |
| US-6506763-B2 | Useful in prevention and treatment of protein kinase related disorders such as cancer | SUGEN, INC. | 2003-01-14 | — | — | US | disclosed |
| US-6133305-A | PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISORDERS SUCH AS CANCER | SUGEN, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| WO-2000053313-A2 | LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES | ARQULE, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149299-A1 | Catalytic osmium-assisted oxidative cleavage of olefins | OXER1, OXSR1, AOX1 | PTPN1 4471/4885PTPN2 4760/4885MAOA 124/4885 |
| US-20090099189-A1 | CRTH2 Receptor Ligands For Medicinal Uses | HRH1, HRH2, HRH3 | PTPN1 3937/4885PTPN2 3736/4885MAOA 3381/4885 |
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | HRH1, HRH2, HRH4 | PTPN1 3876/4885PTPN2 3983/4885MAOA 3509/4885 |
| US-20050197382-A1 | Indolinone combinatorial libraries and related products and methods for the treatment of disease | FRK, PTK2, DSTYK | PTPN1 882/4885PTPN2 1051/4885MAOA 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.