Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.79 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954392 | 0.88 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBERN1 | |
| SCHEMBL1997539 | 0.88 | PTPN1 (1.00) | PTPN1PTPN2MAOAMAOBERN1 | |
| SCHEMBL4010077 | 0.80 | PTPN1 (0.81) | PTPN1PTPN2MAOAMAOBERN1 | |
| SCHEMBL29116218 | 0.79 | PTPN1 (0.50) | PTPN1MAOAMAOBALDH1A1MEN1 | |
| SCHEMBL28564467 | 0.75 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL19182133 | 0.75 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29529294 | 0.75 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29954829 | 0.75 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29958044 | 0.75 | PTPN1 (0.77) | PTPN1PTPN2MAOAMAOBALDH1A1 | |
| SCHEMBL29956322 | 0.75 | PTPN1 (0.61) | PTPN1PTPN2MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |