Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858874 | 0.72 | PTGDR2 (0.49) | KMT2AMEN1LMNAMAPK1RAB9A | |
| SCHEMBL20820013 | 0.72 | MGLL (0.54) | MGLLCHRNA7LDHAKMT2AMEN1 | |
| SCHEMBL28965293 | 0.69 | MGLL (0.51) | MGLLCHRNA7LDHAKMT2AMEN1 | |
| SCHEMBL9860556 | 0.69 | LDHA (0.47) | MGLLCHRNA7LDHAKMT2AMEN1 | |
| SCHEMBL57101 | 0.68 | MEN1 (0.50) | MGLLCHRNA7LDHAKMT2AMEN1 | |
| SCHEMBL17351030 | 0.68 | MGLL (0.46) | MGLLCHRNA7LDHAKMT2AMEN1 | |
| SCHEMBL27514766 | 0.68 | KMT2A (0.51) | MGLLCHRNA7KMT2AMEN1MAPT | |
| SCHEMBL11341571 | 0.68 | MGLL (0.58) | MGLLCHRNA7LDHAKMT2AMEN1 | |
| SCHEMBL26136337 | 0.68 | MGLL (0.67) | MGLLKMT2AMEN1MAPTPOLB | |
| SCHEMBL28167843 | 0.68 | MGLL (0.50) | MGLLCHRNA7LDHAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |