Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014798 | 0.92 | TDP1 (0.54) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL28826273 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL4008815 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL4005562 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL4015320 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL4016056 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL502025 | 0.80 | TDP1 (0.68) | SMN1; SMN2TDP1LMNASCN1ASCN2A | |
| SCHEMBL27215944 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2TDP1MAPTLIN28ALMNA | |
| SCHEMBL4015185 | 0.79 | TDP1 (0.57) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL12807575 | 0.78 | MAPT (0.54) | SMN1; SMN2TDP1MAPTLIN28ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |