Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344056 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL4010249 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTLIN28ATDP1LMNA | |
| SCHEMBL4014798 | 0.79 | TDP1 (0.54) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLIN28A | |
| SCHEMBL4005562 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLIN28A | |
| SCHEMBL28826273 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTLIN28ATDP1LMNA | |
| SCHEMBL4008815 | 0.78 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL4015185 | 0.77 | TDP1 (0.57) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLIN28A | |
| SCHEMBL362970 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAHTTTSHR | |
| SCHEMBL4016056 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 | |
| SCHEMBL27215944 | 0.74 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2MAPTLIN28ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |