Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005562 | 0.87 | SMN1; SMN2 (0.54) | TDP1MAPTSMN1; SMN2LIN28AHDAC3 | |
| SCHEMBL4010249 | 0.79 | SMN1; SMN2 (0.57) | TDP1MAPTSMN1; SMN2LIN28AHDAC3 | |
| SCHEMBL28826273 | 0.79 | SMN1; SMN2 (0.60) | TDP1MAPTSMN1; SMN2LIN28AHDAC3 | |
| SCHEMBL4008815 | 0.79 | SMN1; SMN2 (0.60) | TDP1MAPTSMN1; SMN2LIN28AHDAC3 | |
| SCHEMBL11532136 | 0.78 | TDP1 (0.55) | TDP1SMN1; SMN2HPGDALOX15CYP1A2 | |
| SCHEMBL16488388 | 0.77 | TDP1 (0.70) | TDP1APPALOX5ALDH1A1KDM4E | |
| SCHEMBL4015320 | 0.77 | ALDH1A1 (0.57) | TDP1MAPTSMN1; SMN2LIN28AHPGD | |
| SCHEMBL4016056 | 0.76 | SMN1; SMN2 (0.57) | TDP1MAPTSMN1; SMN2LIN28ACYP1A2 | |
| SCHEMBL22749407 | 0.76 | SMN1; SMN2 (0.60) | TDP1MAPTSMN1; SMN2LIN28AHPGD | |
| SCHEMBL28182817 | 0.76 | TDP1 (1.00) | TDP1MAPTHDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |