Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200212 | 0.85 | TSHR (0.59) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL343520 | 0.83 | TSHR (0.57) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL5202410 | 0.75 | BID (0.66) | PTPN1PTPN2PTPN6BIDBCL2L1 | |
| SCHEMBL6395025 | 0.75 | TSHR (0.56) | TSHRALDH1A1HIF1ACA1CA2 | |
| SCHEMBL23003 | 0.74 | TSHR (0.79) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL23708 | 0.74 | FOLH1 (0.50) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL31090800 | 0.74 | FOLH1 (0.50) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL29367715 | 0.74 | FOLH1 (0.50) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL11322877 | 0.73 | TSHR (0.45) | TSHRPTPN1FOLH1PTPN2PTPN6 | |
| SCHEMBL7642750 | 0.73 | TSHR (0.57) | TSHRPTPN1FOLH1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080744-A1 | CRYSTALLINE FORM OF AZELASTINE | Esteve Química, S.A. (ES) | 2009-07-02 | — | — | WO | disclosed |