Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | BID | P55957 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200212 | 0.98 | TSHR (0.59) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL31090800 | 0.87 | FOLH1 (0.50) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL29367715 | 0.87 | FOLH1 (0.50) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL23708 | 0.87 | FOLH1 (0.50) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL10483666 | 0.85 | TSHR (0.56) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL5553275 | 0.85 | FOLH1 (0.49) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL30232852 | 0.84 | ALDH1A1 (0.70) | TSHRFOLH1PTPN1ALDH1A1 | |
| SCHEMBL4010440 | 0.83 | TSHR (0.47) | TSHRFOLH1PTPN1PTPN2PTPN6 | |
| SCHEMBL7201768 | 0.83 | HTT (0.53) | TSHRFOLH1AKR1C3ALDH1A1ALOX15 | |
| SCHEMBL23003 | 0.83 | TSHR (0.79) | TSHRFOLH1PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016152-A1 | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | SALTIGO GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016152-A1 | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | CYP4B1, HACL2, UGT1A4 | TSHR 2205/4885FOLH1 1070/4885PTPN1 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.