Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617727 | 0.72 | — | — | |
| SCHEMBL17674502 | 0.67 | ALDH1A1 (0.58) | CHRNA7ALDH1A1RAB9A | |
| SCHEMBL4010208 | 0.66 | MGLL (0.44) | CHRNA7MGLLMAPTALDH1A1RAB9A | |
| SCHEMBL9350367 | 0.66 | — | — | |
| SCHEMBL11588947 | 0.66 | EPHX1 (0.44) | CHRNA7MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL20820013 | 0.63 | MGLL (0.54) | CHRNA7MGLLMAPTALDH1A1RAB9A | |
| SCHEMBL1856840 | 0.62 | CHRM2 (0.33) | — | |
| SCHEMBL28965293 | 0.60 | MGLL (0.51) | CHRNA7MGLLMAPTALDH1A1RAB9A | |
| SCHEMBL8045187 | 0.60 | — | — | |
| SCHEMBL29281752 | 0.60 | KMT2A (0.44) | CHRNA7MGLLMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080722-A2 | CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2009-07-02 | — | — | WO | disclosed |