Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 14/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006571 | 0.99 | HSD11B1 (0.43) | HSD11B1SMN1; SMN2TSHRLMNARAB9A | |
| SCHEMBL4003349 | 0.92 | HSD11B1 (0.45) | HSD11B1LMNARAB9A | |
| SCHEMBL4000809 | 0.92 | HSD11B1 (0.45) | HSD11B1LMNARAB9A | |
| SCHEMBL4010765 | 0.90 | HSD11B1 (0.36) | HSD11B1LMNARAB9A | |
| SCHEMBL4003062 | 0.90 | HSD11B1 (0.36) | HSD11B1LMNARAB9A | |
| SCHEMBL4005033 | 0.88 | EPHX2 (0.35) | HSD11B1SMN1; SMN2LMNAEPHX2 | |
| SCHEMBL4010548 | 0.87 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL4003235 | 0.87 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL4004283 | 0.87 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL4005701 | 0.86 | CXCR2 (0.36) | HSD11B1SMN1; SMN2LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | claimed |
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |