Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765107 | 0.88 | HTR6 (0.37) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL4565530 | 0.80 | KAT6A (0.39) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL31039994 | 0.79 | HTR6 (0.44) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL4016980 | 0.76 | F2 (0.44) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL4119819 | 0.75 | TDP1 (0.48) | CA1CA2CA9KMT2AL3MBTL1 | |
| SCHEMBL22829013 | 0.74 | CA1 (0.38) | CA1CA2CA9HTR6SCN5A | |
| SCHEMBL27765108 | 0.74 | CA2 (0.33) | CA1CA2CA9HTR6SCN5A | |
| SCHEMBL11207039 | 0.73 | NPC1 (0.42) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL31708776 | 0.73 | NPC1 (0.42) | CA1CA2MEN1KMT2AL3MBTL1 | |
| SCHEMBL28060767 | 0.73 | HTR6 (0.55) | CA1CA2MEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |