Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007762 | 0.83 | — | — | |
| SCHEMBL8599819 | 0.80 | PLA2G2A (0.44) | MEN1MAPTKMT2AKDM4E | |
| SCHEMBL8596001 | 0.76 | SMN1; SMN2 (0.49) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9143617 | 0.76 | MAPT (0.58) | MEN1MAPTMAPK1RAB9AKMT2A | |
| SCHEMBL9602005 | 0.75 | SMN1; SMN2 (0.51) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL10587724 | 0.75 | SMN1; SMN2 (0.51) | MEN1MAPTMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9439903 | 0.75 | KMT2A (0.58) | MEN1MAPTRAB9AKMT2AKDM4E | |
| SCHEMBL6718844 | 0.75 | MAPT (0.50) | MEN1MAPTMAPK1RAB9AKMT2A | |
| SCHEMBL4157024 | 0.74 | MAPT (0.39) | MEN1MAPTMAPK1RAB9AKMT2A | |
| SCHEMBL4011238 | 0.72 | MAPT (0.55) | MEN1MAPTMAPK1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687307-A4 | SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1687307-A2 | SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS | 3M Innovative Properties Company (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051317-A2 | SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |