Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595814 | 0.82 | KMT2A (0.46) | LMNAKMT2AALDH1A1HTTMEN1 | |
| SCHEMBL8597779 | 0.82 | ESR1 (0.48) | LMNAALDH1A1MAPTHTTGAA | |
| SCHEMBL19876951 | 0.80 | HTT (0.46) | LMNAKMT2AALDH1A1MAPTHTT | |
| SCHEMBL4011235 | 0.80 | MEN1 (0.44) | KMT2AMAPTMEN1KDM4E | |
| SCHEMBL8568499 | 0.79 | POLB (0.46) | KMT2AALDH1A1MAPTHTTMEN1 | |
| SCHEMBL8568264 | 0.79 | POLB (0.41) | ALDH1A1HTTGAACYP1A2POLB | |
| SCHEMBL8569505 | 0.77 | POLB (0.47) | LMNAKMT2AALDH1A1MAPTHTT | |
| SCHEMBL8596247 | 0.77 | MAPT (0.44) | LMNAKMT2AALDH1A1MAPTHTT | |
| SCHEMBL8599650 | 0.77 | CYP1A2 (0.51) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL8602254 | 0.76 | LMNA (0.41) | PLA2G2ALMNAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |