Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.53 |
| ▸ | SARS1 | P49591 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 3/20 | 0.52 |
| ▸ | CD99 | P14209 | 1/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.51 |
| ▸ | IARS1 | P41252 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619720 | 0.88 | CA1 (0.49) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL11517589 | 0.84 | ADORA3 (0.65) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL11517600 | 0.84 | ADORA3 (0.65) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL4010175 | 0.84 | AHCY (0.64) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL11519330 | 0.81 | ADORA3 (0.63) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL2460500 | 0.79 | P2RY1 (0.58) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL258935 | 0.79 | ADORA3 (0.59) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL2489469 | 0.78 | CA1 (1.00) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL2489474 | 0.78 | CA1 (1.00) | CA1CA2CA4CA9ADORA3 | |
| SCHEMBL29737838 | 0.78 | CA1 (1.00) | CA1CA2CA4CA9ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| EP-2074126-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008049105-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | CA1 4466/4885CA2 4557/4885CA4 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.