Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 10/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.64 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.60 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8142114 | 0.91 | PRMT5 (0.63) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL31001599 | 0.88 | ADORA3 (0.60) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL31680251 | 0.87 | AHCY (0.68) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL397800 | 0.87 | AHCY (0.68) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL7803295 | 0.86 | AHCY (0.67) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL6671788 | 0.86 | AHCY (0.67) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL2040666 | 0.85 | PRMT5 (0.66) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL3904194 | 0.84 | PRMT5 (0.55) | AHCYADORA2AADORA2BHSP90B1HIF1A | |
| SCHEMBL4011368 | 0.84 | CA1 (0.64) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10619720 | 0.84 | CA1 (0.49) | AHCYADORA2AADORA2BHSP90B1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946188-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-01-23 | — | — | US | disclosed |
| US-8461128-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-06-11 | — | — | US | disclosed |
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-07-02 | — | — | US | disclosed |
| EP-2074126-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008049105-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
| WO-2006113615-A2 | ANTI-MICROBIAL AGENTS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2006-10-26 | — | — | WO | disclosed |
| US-4992426-A | Antiparasitic 5'-sulfamoyl nucleosides | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | ACAT1, ACAT2, APEH | AHCY 30/4885ADORA2A 653/4885ADORA2B 1427/4885 |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | AHCY 2042/4885ADORA2A 4635/4885ADORA2B 4770/4885 |
| US-20090170805-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | ACAT1, ACAT2, APEH | AHCY 30/4885ADORA2A 653/4885ADORA2B 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.