Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666238 | 0.81 | TLR3 (0.43) | TLR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7608955 | 0.77 | MAPT (0.46) | TLR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13090968 | 0.77 | KMT2A (0.46) | TLR3MEN1KMT2AMAPTGAA | |
| SCHEMBL6937137 | 0.77 | KCNE1 (0.55) | TLR3MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL3319434 | 0.76 | KCNE1 (0.44) | TLR3MEN1KMT2AKCNE1KCNQ1 | |
| SCHEMBL3319440 | 0.76 | KCNE1 (0.44) | TLR3MEN1KMT2AKCNE1KCNQ1 | |
| SCHEMBL9141913 | 0.76 | TLR3 (0.43) | TLR3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6938486 | 0.75 | KCNE1 (0.57) | TLR3MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL31260267 | 0.74 | MAPT (0.47) | TLR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2353554 | 0.74 | TLR3 (0.41) | TLR3MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |