Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012114 | 0.83 | TRPA1 (0.49) | PDE10AMAPTTRPA1SLC6A4HTR1A | |
| SCHEMBL4007180 | 0.82 | TRPA1 (0.57) | CARM1PDE10APRMT6MAPTTRPA1 | |
| SCHEMBL4007110 | 0.81 | SLC6A4 (0.47) | P2RY1MAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4008185 | 0.80 | PDE10A (0.44) | P2RY1CARM1PDE10APRMT6MAPT | |
| SCHEMBL11924845 | 0.77 | CARM1 (0.65) | P2RY1CARM1PRMT6MAPTTRPA1 | |
| SCHEMBL30593115 | 0.76 | CYP1A2 (0.41) | TRPA1SLC6A4HTR2AKCNH2PKM | |
| SCHEMBL26608264 | 0.76 | CYP1A2 (0.41) | TRPA1SLC6A4HTR2AKCNH2PKM | |
| SCHEMBL4015050 | 0.74 | HTR1A (0.60) | P2RY1MAPTSLC6A4HTR1ASLC6A2 | |
| SCHEMBL13769647 | 0.74 | HTR1A (0.76) | SLC6A4HTR1ASLC6A2SLC6A3 | |
| SCHEMBL4007377 | 0.73 | HPGD (0.49) | MAPTSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |