Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13961400 | 1.00 | ACHE (0.60) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12477497 | 0.83 | POLB (0.47) | USP2MAPTPOLB | |
| SCHEMBL5506588 | 0.81 | ACHE (0.62) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13961390 | 0.80 | ACHE (0.40) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11053382 | 0.76 | ACHE (0.59) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13961415 | 0.76 | ALDH1A1 (0.39) | ACHEBCHEALDH1A1KMT2AMEN1 | |
| SCHEMBL5511124 | 0.75 | ACHE (0.69) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29638891 | 0.75 | ACHE (1.00) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3892901 | 0.75 | ACHE (1.00) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13960728 | 0.75 | ALDH1A1 (0.34) | ACHEBCHEALDH1A1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015179-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009015179-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |